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Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men's body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.
The new prevalence away from sterility among couples off reproductive age brackets, according to various present, away from 8% to twenty five% [1–3]. Men sterility is the merely factor in sterility in 20–30% out-of cases and you will a very important factor leading to infertility in the 50% of all of the infertility circumstances . This new comparison out of male fertility always has scientific test and you can analysis into site thinking of the after the semen parameters: regularity, total sperm fertility, focus, motility and you can morphology (Table step 1) . Lowest sperm count and you can/otherwise quality can be acquired within the ninety% from people having fertility dilemmas . On review out of fertility, new density off male reproductive hormones also are assessed. Recently, the latest molecular composition away from jizz muscle, examined by comparing the amount of DNA fragmentation or oxidative fret could have been all the more taken into account. Numerous degree make use of the DNA fragmentation list (DFI) just like the a sign of being pregnant achievements. Considering Evenson and Wixon, DFI range of three to five% during the compliment guys, when you are a great DFI of ? 30% try of less virility . Currently outlined genetic situations, and additionally each other chromosomal aberrations and monogenic transform, account fully for just about ten–15% off instances of male infertility . The cause to possess virility trouble can certainly be environmental things. The goal of the analysis was to get to know the relationship ranging from diet, energy equilibrium and you can fertility prices into the males.
A comprehensive literature search of published studies in various languages, was carried out in electronic databases, including: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Review and Google Scholar. Randomized controlled trials, observational and qualitative studies published between 2008 and 2018 (up to and including March) were included. The following keywords related to male infertility, diet, nutrients and their combinations (made by applying operators AND and OR) were used in the search: ‘male infertility’, ‘sperm quality’, ‘idiopathic oligozoospermia’, ‘astenoazospermia’, ‘oligoastenoteratozoospermia’, ‘sperm DNA damage’, ‘nutritional status’, ‘BMI’, ‘obesity’, ‘diet’, ‘nutrition’, dietary pattern’, ‘food’, ‘nutrient’, ‘fatty acids’, ‘antioxidant’, ‘supplementation’, ‘vitamin C’, ‘vitamin E’,’ vitamin A’, ‘folate’, ‘zinc’, ‘selenium’, ‘L-carnitine’, ‘glutathione’, ‘coenzyme Q10‘, ‘N-acetylcysteine’, ‘lycopene’. Reference lists of studies extracted from the primary electronic search were used to identify additional relevant studies.
Semen parameter | Site restriction (95% rely on durations) |
---|---|
Sperm frequency | step one.5 ml (step 1.4–step 1.7) |
Full sperm fertility | 39 million for each and every ejaculate (33–46) |
Cum focus | 15 escort girl Phoenix mil for each ml (12–16) |
Efforts | 58% alive (55–63) |
Progressive motility | 32% (31–34) |
Total (modern + nonprogressive) motility | 40% (38–42) |
Morphologically regular variations | 4.0% (step 3.0–4.0) |
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