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The majority of participants were black (68.6 per cent; 24.1 per cent white, 2.9 per cent Asian, 4.4 per cent multiracial/other) and female (86.1 per cent). Mean participant age was 46.1 ± 10.1 years, and mean BMI at baseline was 40.8 ± 5.9 kg/m 2 . 3 ± 2.9 per cent of initial weight (10.7 ± 4.0 kg). At week 52 of the weight loss maintenance RCT (i.e., 66 weeks total), lorcaserin-treated participants maintained an average loss of 7.8 ± 0.8 per cent of escort reviews Miami initial body weight (9.4 ± 0.9 kg), as measured from the start of the LCD program, compared with 6.6 ± 0.9 per cent (7.5 ± 1.0 kg) for those on placebo. As previously reported [ 18], lorcaserin-treated patients achieved a greater weight loss at week 24 of the RCT than participants who received placebo (11.7 vs. 8.4 per cent of initial body weight, p ?5 , SEb = 0.0001, p = .54; weight ? time 2 b = 3.35 ? 10 ?6 , SEb = 2.93 ? 10 ?6 , p = .25. (The effect of percent weight change on WBI, controlling for baseline BMI rather than height, was also tested and showed no significant effects.) Race did not significantly interact with WBIS scores or time. Overall, WBIS scores decreased by 0.40 points (SD = 0.92) from baseline to week 52 of the RCT (i.e., 66 weeks total): baseline M = 3.69 ± 1.14 (N = 133), week 14 M = 3.23 ± 1.21 (N = 137), week 24 of RCT M = 2.97 ± 1.26 (N = 105), and week 52 of RCT M = 3.23 ± 1.32 (N = 90).
Logistic regression results showed that, from the times twenty-four of RCT, large standard WBIS ratings predicted 37 percent quicker odds of achieving ?5 percent diet (p = .012) and 34 percent smaller likelihood of finding ?10 % dieting (p = .022; Table step 1). So it feeling was not tall from the week 52 to own pounds losses regarding ?5 per cent (p = .48) otherwise ?10 percent (p = .13), neither having ?10 percent weightloss within month 14 (p = .22). e., 66 months overall; Otherwise = dos.twenty seven, 95% CI = step 1.01, 5.09, p = .046). Certainly nonblack members, high standard WBIS ratings was of 62 per cent down odds (95% CI = 0.19, 0.80, p = .01) of reaching ?ten % diet within times 52, while zero effectation of baseline WBIS scores on weightloss is actually discovered for black colored participants (p = .94). Baseline WBIS ratings don’t notably connect with race so you’re able to assume ?5 or ?ten % weight reduction any kind of time other time section.
Body mass index bmi; Lcd lowest-fat diet plan; RCT randomized managed demonstration. All of the continuous predictor details was indeed depending in the the mode.
Bmi bmi; Liquid crystal display low-fat diet plan; RCT randomized regulated trial. Every continuous predictor variables was basically centered within its form.
The linear mixed model found no significant effect of baseline WBIS scores on rate of weight change at week 14 (b = ?0.002, SEb = 0.02, p = .91), or at week 24 (b = 0.03, SEb = 0.03, p = .23) or 52 (b = 0.002, SEb = 0.01, p = .90) of the RCT. Additionally, no significant interaction between race and WBI was found.
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